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All You Need To Know About Cervical Cancer.

Cervical cancer is a type of cancer that originates in the cervix, the lower part of the uterus that connects to the vagina. This form of cancer usually develops slowly over several years, beginning with abnormal cell changes known as dysplasia. If left untreated, these abnormal cells can evolve into cervical cancer.

The cervix plays a big role in a woman's reproductive system, it serves as the gateway through which sperm must travel to fertilize an egg during conception. In order to fully understand cervical cancer, one needs to be aware of  the factors that contribute to its development, the risks involved, and the treatment options.

Cervical cancer is a significant health concern worldwide, but it is also one of the most preventable and treatable forms of cancer when discovered early. One of the primary reasons for its preventability lies in its well-established link to the Human Papillomavirus (HPV). HPV is a common sexually transmitted infection that can lead to cervical cancer. 

In Nigeria, cervical cancer ranks as the third most prevalent cancer and the second leading cause of cancer-related deaths among women aged 15 to 44. In 2020 alone, Nigeria witnessed 12,000 new cases and 8,000 fatalities attributed to cervical cancer.

Cervical cancer awareness also extends to destigmatizing conversations around reproductive health. Open dialogue encourages individuals to seek medical help without hesitation, promoting early diagnosis and timely intervention. This article aims to discuss cervical cancer, from its causes to prevention, diagnosis, treatment, and support.

How HPV (Human Papillomavirus) Causes Cervical Cancer Development

Cervical cancer is closely linked to the Human Papillomavirus (HPV), a group of viruses that infect the genital area. HPV is incredibly common, and while most infections clear on their own, persistent infections with certain high-risk HPV types can lead to cervical cancer over time.

HPV is primarily transmitted through sexual contact, and anyone who has ever been sexually active can contract the virus. The body's immune system can usually clear the infection, but if the virus persists, it can cause changes in cervical cells that may eventually lead to cancer. 

High-risk HPV types, particularly HPV 16 and HPV 18, are responsible for the majority of cervical cancer cases. These viruses can integrate into the DNA of cervical cells, disrupting the normal cell cycle and leading to the formation of cancerous cells.

It's important to note that having HPV doesn't mean an individual will develop cervical cancer. Most HPV infections clear up on their own, but regular screenings must be done to detect and address abnormal changes in cervical cells early, preventing the progression to cancer.

Other Risk Factors for Cervical Cancer

While HPV is the primary risk factor for cervical cancer, other factors can increase the likelihood of its development. These include:

  1. Smoking:

Smoking tobacco is associated with an increased risk of cervical cancer. Chemicals in tobacco can damage cervical cells and contribute to the progression of precancerous lesions.

  1. Weakened Immune System:

Individuals with weakened immune systems, such as those with HIV or taking immunosuppressive medications, are at higher risk. A high immune system can hep suppress HPV infections.

  1. Long-Term Use of Birth Control Pills:

Long-term use of oral contraceptives has been linked to a slightly increased risk of cervical cancer. However, the risk decreases once the pills are discontinued.

  1. Multiple Full-Term Pregnancies:

Women who have had three or more full-term pregnancies may have an increased risk, possibly due to hormonal changes during pregnancy.

Prevention and Screening Of Cervical Cancer

The Human Papillomavirus (HPV) vaccine can help in the fight against cervical cancer. It is a powerful preventive tool designed to protect against the most common types of high-risk HPV, including those responsible for the majority of cervical cancer cases. The vaccine is typically administered in two or three doses, depending on age and health factors.

The primary goal of the HPV vaccine is to confer immunity against the virus before any potential exposure. By vaccinating individuals before they become sexually active, especially during adolescence, we can significantly reduce the risk of HPV infection and, subsequently, cervical cancer. It's a proactive approach that emphasizes prevention over treatment.

Importance of Regular Pap Smear Tests

Pap smear tests, also known as Pap tests or cervical cytology, can be used for cervical cancer screening. This simple and quick procedure involves collecting a small sample of cells from the cervix, which is then examined under a microscope for any abnormalities.

Pap smear testing is commonly used to detect cervical cancer early, allowing healthcare providers to identify abnormal cervical cells before they become cancerous. Regular screenings enable timely intervention, often preventing the progression to cervical cancer.

While highly effective, Pap smears may not detect all cases of cervical cancer or precancerous lesions. In order to be on the safe side, you can combine Pap smears with other screening methods for better results.

Diagnosis and Staging of Cervical Cancer

Cervical cancer, in its early stages, is often asymptomatic. As the disease progresses, certain clinical features and symptoms may begin to manifest. These can include abnormal vaginal bleeding, pelvic pain, pain during intercourse, and unusual vaginal discharge.

It's important for individuals to pay attention to their bodies and promptly report any unusual changes or discomfort to their healthcare providers. 

Cervical Cancer Staging Process

Upon the diagnosis of cervical cancer, healthcare professionals use a staging system to determine the extent of the disease. The staging process assesses the size of the tumor, its invasion into surrounding tissues, and whether it has spread to lymph nodes or other parts of the body.

The International Federation of Gynecology and Obstetrics (FIGO) staging system is commonly used for cervical cancer. It categorizes the disease into four stages:

Stage I: Cancer is confined to the cervix.

Stage II: Cancer has spread beyond the cervix but not to the pelvic sidewall or lower third of the vagina.

Stage III: Cancer has invaded the pelvic sidewall or lower third of the vagina.

Stage IV: Cancer has spread to nearby organs or distant parts of the body.

Treatment Options for Cervical Cancer

The choice of treatment for this disease depends on the stage of cancer, the extent of spread, the individual's health, and personal preferences.

Surgical Options for Cervical Cancer

Surgery is a common treatment for cervical cancer, especially in its early stages. The type of surgery depends on the extent of the cancer:

  1. Conization: Removal of a cone-shaped piece of tissue containing the abnormal cells.
  2. Hysterectomy: Removal of the uterus and possibly surrounding tissues, such as the ovaries and nearby lymph nodes.
  3. Surgery aims to remove the cancerous cells while preserving as much healthy tissue as possible. The choice of surgical intervention depends on factors like the size and location of the tumor and the individual's reproductive goals.

Radiation Therapy for Cervical Cancer Treatment

Radiation therapy employs high-energy rays to destroy cancer cells. In cervical cancer, it is often used in conjunction with surgery or as the primary treatment for more advanced cases. 

There are two main types of radiation therapy:

  1. External Beam Radiation: Directing radiation from outside the body to the tumor.
  2. Brachytherapy: Placing a radiation source directly inside or very close to the tumor.

Radiation therapy is particularly effective in treating localized cancer and targeting areas where surgery may not be feasible.

Chemotherapy and Targeted Therapy for Cervical Cancer

Chemotherapy is the use of drugs to kill or inhibit the growth of cancer cells throughout the body. It is an effective form of treatment, it also affects normal, healthy cells, leading to potential side effects. Targeted therapy, on the other hand, focuses on specific molecules involved in cancer growth, minimizing damage to healthy cells.

These approaches are often used in advanced cases of cervical cancer or when the disease has spread to other parts of the body.

Model of a human uterus in the hands of a Gynaecologist close-up. Pharmarun | Online Pharmacy In Nigeria

Frequently Asked Questions about Cervical Cancer

Question: What is the HPV vaccine, and is it safe?

Answer: The HPV vaccine is a highly effective preventive measure against the Human Papillomavirus (HPV), a leading cause of cervical cancer. It is safe and has undergone rigorous testing. The vaccine is recommended for both males and females, typically administered during adolescence to provide immunity before potential exposure to the virus.

Question: How accurate are Pap smear tests in detecting cervical cancer?

Answer: Pap smear tests can help with early detection, but they are not infallible. While highly accurate, they may not detect all cases. You may have to combine Pap smears with HPV testing and regular check-ups to get a better result.

Question: What are the key symptoms of cervical cancer?

Answer: In its early stages, cervical cancer may be asymptomatic. As the disease progresses, symptoms may include abnormal vaginal bleeding, pelvic pain, pain during intercourse, and unusual vaginal discharge. It is important for every woman to have regular check-ups and screenings for early detection, as symptoms may not appear until the later stages.

Question: Is the HPV vaccine only for young individuals, or can adults get vaccinated too?

Answer: While the HPV vaccine is most effective when administered before potential exposure to the virus, adults can still benefit from vaccination. It is recommended for individuals up to age 45, and discussions with healthcare providers can help determine the appropriateness of vaccination based on individual circumstances.

Question: How is cervical cancer staged, and why is staging important?

Answer: Cervical cancer is staged using the FIGO system, which assesses the size of the tumor, invasion into surrounding tissues, and spread to lymph nodes or other organs. Staging is important for developing an effective treatment plan tailored to the specific characteristics of the disease. It guides healthcare professionals in determining the best course of action for optimal outcomes.

Question: Can cervical cancer be treated successfully?

Answer: Yes, the success of treatment depends on factors such as the stage of cancer, overall health, and the chosen treatment plan. Early detection significantly improves the chances of successful treatment and recovery. Treatment options may include surgery, radiation therapy, chemotherapy, and targeted therapy, often tailored to the individual's unique circumstances.

Question: How can I access financial assistance for cervical cancer treatment?

Answer: There are numerous nonprofit organizations and financial assistance programs for supporting cancer patients. These organisations may offer help with medical bills, prescription medications, and other related expenses. 

Here are some financial support organisations you can check out

  1. Global Health Progress
  2. Medicaid Cancer Foundation
  3. The Dorcas Cancer Foundation
  4. St Cyril Cancer Treatment Foundation

Question: What role do support groups play in the cervical cancer journey?

Answer: Support groups offer supportive community for individuals facing cervical cancer. Sharing experiences, coping strategies, and emotional support can help get rid of any feeling of isolation. Additionally, engaging with support groups can provide valuable insights into managing the emotional aspects of living with cancer.

Click here to join the Pharmarun Cancer Support Group.

Question: How can survivors transition back to a fulfilling life after treatment?

Answer: Rehabilitation and survivorship programs can help individuals regain physical strength and functionality after treatment. These programs focus on long-term health, emotional well-being, and strategies for transitioning back to a fulfilling life post-treatment.

Question: How can you prevent cervical cancer?

Answer: Prevention starts with education, awareness, and proactive measures. You can also receive the HPV vaccine, undergoing regular screenings, and adopting a healthy lifestyle.

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